Few infectious diseases have been eradicated, and their steady global spread is favored by changing climatic conditions, increased migration of infected individuals and disease vectors, or the spread of drug resistance. New variants of infectious agents pose a continuous threat and so does the (re)emergence of pathogens. To tackle these problems, understanding the intricacies of host-pathogen interactions is key to combating disease.
Research of the Host-Pathogen Focus includes basic studies on the strategies used by pathogens to invade and persist in the infected animal, and on the cellular and molecular mechanisms underlying the disease pathogenesis. Application-oriented research addresses questions of molecular epidemiology, vaccine development, drug development and resistance, and the diagnostics for animal pathogens.